System and method for evaluating cellular and tissue dynamics
US Patent 11,986,400
Granted: May 2024
Publications & Research
Peer-reviewed publications spanning computational biology, GPU computing, and machine learning
📄 Download Full CV📊 Research Impact
25+
Publications
5
Nature Journals
12+
Years Research
170+
Scientists Advised
3
Patents
Patents
System and method for evaluating cellular and tissue dynamics
US Patent 11,406,536
Granted: August 2022
System and method for evaluating cellular and tissue dynamics
US Patent 11,116,669
Granted: September 2021
Peer Reviewed Publications
2024
Assessing cell viability with dynamic optical coherence microscopy
Liu C, Smith J, Wang Y, Ouellette J, Rogers J, Oliner J, Szulczewski M, Wait E, Brown W, Wax A, Eliceiri K, Rafter J
Biomedical Optics Express
Four-dimensional quantitative analysis of cell plate development in Arabidopsis using lattice light sheet microscopy
Sinclair R, Wang M, Jawaid M Z, Longkumer T, Aaron J, Rossetti B, Wait E, McDonald K, Cox D, Heddleston J
Journal of Experimental Botany
Distinct mobility patterns of BRCA2 molecules at DNA damage sites
Paul M, Aaron J, Wait E, Van Genderen R, Tyagi A, Kabbech H, Smal I, Chew T.-L., Kanaar R, Wyman C
Nucleic Acids Research
2023
Dissecting Cell Plate Development During Plant Cytokinesis
Sinclair R, Cox D, Heddleston J, Aaron J, Wait E, Wilkop T, Drakakaki G
Microscopy and Microanalysis
2022
Myosin VI Regulates the Spatial Organization of Mammalian Transcription Initiation
Hari-Gupta Y, Fili N, dos Santos Á, et al.
Nature Communications
Binding partners regulate unfolding of myosin VI to activate the molecular motor
Dos Santos Á, Fili N, Hari-Gupta Y, et al.
Biochemical Journal
Quantifying Molecular Dynamics within Complex Cellular Morphologies using LLSM FRAP
Colin‐York H, Heddleston J, Wait E, et al.
Small Methods
2021
Actin cables and comet tails organize mitochondrial networks in mitosis
Moore A, Coscia S, Simpson C, et al.
Nature
Endothelial Junctional Membrane Protrusions Serve As Hotspots for Neutrophil Transmigration
Arts J, Mahlandt E, Grönloh M, et al.
eLife
3D image analysis of the complete ventricular-subventricular zone stem cell niche
Zhao X, Wang Y, Wait E, et al.
Stem Cell Reports
2020
Hypothesis-Driven Quantitative Fluorescence Microscopy: The Importance of Reverse-thinking in Experimental Design
Wait E, Reiche M, Chew T.-L.
Journal of Cell Science
FMNL2 Regulates Dynamics Of Fascin In Filopodia
Pfisterer K, Levitt J, Lawson CD, et al.
Journal Cell Biology
2019
Hydra Image Processor: 5-D GPU image analysis library with MATLAB and python wrappers
Wait E, Winter M, Cohen A R
Bioinformatics
Practical Considerations in Particle and Object Tracking and Analysis
Aaron J, Wait E, DeSantis M, Chew T.-L.
Current Protocols Cell Biology
2018
Separating Touching Cells using Pixel Replicated Elliptical Shape Models
Winter M, Mankowski W, Wait E, et al.
IEEE Transactions on Medical Imaging
2017
Applying Systems-level Spectral Imaging and Analysis to Reveal the Organelle Interactome
Valm A, Cohen S, Legant W, et al.
Nature
2016
A Neuronal Network Of Mitochondrial Dynamics Regulates Metastasis
Caino C, Seo J, Aguinaldo A, Wait E, et al.
Nature Communications
LEVER: software tools for segmentation, tracking and lineaging of proliferating cells
Winter M, Mankowski W, Wait E, Temple S, Cohen A
Bioimage Informatics
2015
Segmentation, Tracking and Lineaging of Proliferating Cells from 2-D to 5-D
Wait E, Mankowski W, Winter M, et al.
Focus on Microscopy
Collaborative Visualization in the Browser for Segmentation, Tracking, and Lineaging with 5-D Biological Microscopy Images
Wait E, Winter M, Song S, et al.
BioImage Informatics Conference
Normalized Covariance Image Stitching Technique for Rigid Registration of Microscope Tiles
Wait E, Winter M, Cohen A
BioImage Informatics Conference
2014
Visualization and Correction of Automated Segmentation, Tracking and Lineaging from 5-D Stem Cell Image Sequences
Wait E, Winter M, Bjornsson C, et al.
BMC Bioinformatics
Segmentation of occluded hematopoietic stem cells from tracking
Mankowski W C, Winter M R, Wait E, et al.
IEEE EMBC
2011
Vertebrate Neural Stem Cell Segmentation, Tracking And Lineaging With Validation And Editing
Winter M, Wait E, Roysam B, et al.
Nature Protocols
For a complete overview of research, experience, and achievements
📄 Download Complete CVResearch Areas
🧬
Computational Biology
Image analysis, cell tracking, quantitative microscopy
⚡
GPU Computing
CUDA acceleration, real-time processing, optimization
🤖
Machine Learning
Physics-informed ML, domain-aware architectures